DOI: 10.1553/skindeep.2025.169584

Authors: Sophie Marie Sinz, Ulrich Koller, Bernadette Liemberger, Stefan Hainzl, Alfred Klausegger, Joerg von Hagen, Norbert Müller, Thomas Mohr, Christopher Gerner, Gazmend Temaj, Martin Laimer, Hannelore Breitenbach-Koller, Johann W. Bauer

Abstract: Treating severe junctional epidermolysis bullosa with artesunate

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DOI: 10.1553/skindeep.2025.150947

Authors: Antonella Muñoz, Evelyng Catalán, Maria-Laura Cossio, Francis Palisson, Ignacia Fuentes

Abstract: Epidermolysis Bullosa (EB) is a rare genetic disorder characterized by skin and mucous membrane fragility. Oxidative stress is recognized as a major factor contributing to persistent and recurrent lesions. It can induce genomic damage, protein oxidation, lipid peroxidation, pathological angiogenesis and hypoxia. Despite the severity of the condition, therapeutic options remain limited. Here we explore the potential role of antioxidant compounds in EB patients, incorporating these compounds as a novel cornerstone in EB management.

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