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  • Article title
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  • 1. Introduction
  • 2. Studies on the effects of seasonal changes on skin diseases
  • 3. Animal and epidermal equivalent models and human studies examined the effects of a dry environment
    • 3.1 Dry conditions and barrier function
    • 3.2 Effects of drastic decrease of humidity
    • 3.3 Inflammatory responses to dry environment
  • 4. Itch
  • 5. Epidermal sensory system
  • 6. Skin-brain axis
  • 7. Conclusion
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